| Product Code: ETC9970281 | Publication Date: Sep 2024 | Updated Date: Nov 2025 | Product Type: Market Research Report | |
| Publisher: 6Wresearch | Author: Dhaval Chaurasia | No. of Pages: 75 | No. of Figures: 35 | No. of Tables: 20 |
The United States saw significant growth in methotrexate injection import shipments in 2024, with top exporting countries including Switzerland, Ireland, Singapore, India, and Germany. The market concentration, as measured by the HHI, decreased from moderate to low in 2024. With a healthy CAGR of 2.85% from 2020 to 2024 and a notable growth rate of 7.62% from 2023 to 2024, the US market for methotrexate injections is showing promising trends for the future.

1 Executive Summary |
2 Introduction |
2.1 Key Highlights of the Report |
2.2 Report Description |
2.3 Market Scope & Segmentation |
2.4 Research Methodology |
2.5 Assumptions |
3 United States (US) Methotrexate Injection Market Overview |
3.1 United States (US) Country Macro Economic Indicators |
3.2 United States (US) Methotrexate Injection Market Revenues & Volume, 2021 & 2031F |
3.3 United States (US) Methotrexate Injection Market - Industry Life Cycle |
3.4 United States (US) Methotrexate Injection Market - Porter's Five Forces |
3.5 United States (US) Methotrexate Injection Market Revenues & Volume Share, By Type, 2021 & 2031F |
3.6 United States (US) Methotrexate Injection Market Revenues & Volume Share, By Route of Administration, 2021 & 2031F |
3.7 United States (US) Methotrexate Injection Market Revenues & Volume Share, By End-Users, 2021 & 2031F |
4 United States (US) Methotrexate Injection Market Dynamics |
4.1 Impact Analysis |
4.2 Market Drivers |
4.2.1 Increasing incidence of autoimmune diseases such as rheumatoid arthritis |
4.2.2 Rising geriatric population in the United States |
4.2.3 Growing awareness about the effectiveness of methotrexate injections in treating various conditions |
4.3 Market Restraints |
4.3.1 Stringent regulatory requirements for drug approval and manufacturing |
4.3.2 Competition from alternative treatment options such as biologics |
4.3.3 Concerns regarding potential side effects and toxicity associated with methotrexate use |
5 United States (US) Methotrexate Injection Market Trends |
6 United States (US) Methotrexate Injection Market, By Types |
6.1 United States (US) Methotrexate Injection Market, By Type |
6.1.1 Overview and Analysis |
6.1.2 United States (US) Methotrexate Injection Market Revenues & Volume, By Type, 2021- 2031F |
6.1.3 United States (US) Methotrexate Injection Market Revenues & Volume, By Branded, 2021- 2031F |
6.1.4 United States (US) Methotrexate Injection Market Revenues & Volume, By Generics, 2021- 2031F |
6.2 United States (US) Methotrexate Injection Market, By Route of Administration |
6.2.1 Overview and Analysis |
6.2.2 United States (US) Methotrexate Injection Market Revenues & Volume, By Intramuscular, 2021- 2031F |
6.2.3 United States (US) Methotrexate Injection Market Revenues & Volume, By Subcutaneous, 2021- 2031F |
6.2.4 United States (US) Methotrexate Injection Market Revenues & Volume, By Others, 2021- 2031F |
6.3 United States (US) Methotrexate Injection Market, By End-Users |
6.3.1 Overview and Analysis |
6.3.2 United States (US) Methotrexate Injection Market Revenues & Volume, By Hospitals, 2021- 2031F |
6.3.3 United States (US) Methotrexate Injection Market Revenues & Volume, By Specialty Clinics, 2021- 2031F |
6.3.4 United States (US) Methotrexate Injection Market Revenues & Volume, By Others, 2021- 2031F |
7 United States (US) Methotrexate Injection Market Import-Export Trade Statistics |
7.1 United States (US) Methotrexate Injection Market Export to Major Countries |
7.2 United States (US) Methotrexate Injection Market Imports from Major Countries |
8 United States (US) Methotrexate Injection Market Key Performance Indicators |
8.1 Patient adherence rate to methotrexate treatment plans |
8.2 Number of clinical trials and research studies on methotrexate efficacy and safety |
8.3 Prescription renewal rates for methotrexate injections |
9 United States (US) Methotrexate Injection Market - Opportunity Assessment |
9.1 United States (US) Methotrexate Injection Market Opportunity Assessment, By Type, 2021 & 2031F |
9.2 United States (US) Methotrexate Injection Market Opportunity Assessment, By Route of Administration, 2021 & 2031F |
9.3 United States (US) Methotrexate Injection Market Opportunity Assessment, By End-Users, 2021 & 2031F |
10 United States (US) Methotrexate Injection Market - Competitive Landscape |
10.1 United States (US) Methotrexate Injection Market Revenue Share, By Companies, 2024 |
10.2 United States (US) Methotrexate Injection Market Competitive Benchmarking, By Operating and Technical Parameters |
11 Company Profiles |
12 Recommendations |
13 Disclaimer |
Export potential enables firms to identify high-growth global markets with greater confidence by combining advanced trade intelligence with a structured quantitative methodology. The framework analyzes emerging demand trends and country-level import patterns while integrating macroeconomic and trade datasets such as GDP and population forecasts, bilateral import–export flows, tariff structures, elasticity differentials between developed and developing economies, geographic distance, and import demand projections. Using weighted trade values from 2020–2024 as the base period to project country-to-country export potential for 2030, these inputs are operationalized through calculated drivers such as gravity model parameters, tariff impact factors, and projected GDP per-capita growth. Through an analysis of hidden potentials, demand hotspots, and market conditions that are most favorable to success, this method enables firms to focus on target countries, maximize returns, and global expansion with data, backed by accuracy.
By factoring in the projected importer demand gap that is currently unmet and could be potential opportunity, it identifies the potential for the Exporter (Country) among 190 countries, against the general trade analysis, which identifies the biggest importer or exporter.
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